Starna Scientific Ltd.

Starna Scientifics’s Certified Reference Materials (CRM) for fluorescence spectroscopy have been specifically designed and developed for applications that require day-to-day validation and long term monitoring of fluorescence system responsivity.

Starna Fluorescent references are frequently used in the following types of system:

• Spectroflurometer
• ELISA fluorescent plate-readers
• PCR systems
• Point-of-care fluorescent based systems

Measurements on fluorescence based measurement systems are typically subject to a large number of instrumental variables. A given sample may give significantly different results when measured on different instruments even if they are of similar design.

The measurable signal of fluorescent analytes can be impacted by a number of chemical and physical effects, such as quenching or self-absorption of the fluorescence emission, which may lead to departures from the expected concentration/emission relationships outside of a narrow range. Additionally, many fluorescent materials are susceptible to photobleaching, such that detectable signal may noticeably fade with repeated measurement.

Therefore, to ensure confidence in results, a stable and consistent point of measurement reference should be used minimise or remove the effects of these variables.

Where applicable, specific properties of fluorescent CRM can be made tracible to NIST Standard Reference Materials in our ISO/IEC 17025 calibration laboratory.

All fluorescent CRM are manufactured in our ISO 17034 accredited Reference Material Production facility.

Starna is the World’s Leading Supplier of Certified Reference Materials (CRMs) for Spectroscopy
• References for all wavelengths, from Deep UV to Mid Infrared
• References for Fluorescence, Life Science and Microvolume applications
• Liquid and vapour references permanently heat sealed into Starna cuvettes for stability, safety and durability
• Lifetime Guarantee on all CRMs
• Fast recalibration service
• Technical support and advice

Flow cells are used for measuring samples with continuous flow or sipper systems where individual samples are aspirated into the cell. For example:

• Tablet dissolution
• Clinical chemistry systems
• Blood analysers
• Urine analysers
• Flow microscopy

They are also used in sipper systems where individual samples are aspirated into the cell. Flow cells are made in a wide array of designs because each application has a different compromise of sample volume, flow pattern, pathlength and tubing requirements. We make a wide range of flow cells and have made every effort to simplify the process of selection as much as possible. If you have questions, please e-mail us and we will answer your technical questions promptly.

The DMV Bio-cell from Starna is the elegant solution to direct, accurate measurement of nucleic acids or proteins in low volume biological samples. The Bio-cell is compatible with any conventional UV spectrophotometer and its magnetic closure design facilitates rapid filling and emptying and easy cleaning, providing cost-effective, easy-to-use low-volume analysis. For those working in the regulated environment, Starna's expertise in cell technology is combined with Performance Qualification using specially developed Certified Reference Materials to give truly validated measurements and the ultimate confidence in results.

Direct low volume analysis of nucleic acids and proteins
Available with 2.5, 1.0 and 0.6 μl volumes
High accuracy and reproducibility
Validated measurements
Certified Reference Materials for OQ/PQ
Certified path length option
Compatible with all major UV/Visible spectrophotometers

Precision micro-machining techniques and advanced materials are used to create a patented high energy optical system, so that low volume samples can be measured accurately and reproducibly across a wide absorbance range. The DMV-Bio Cell is available in 0.5, 0.2 and 0.125 mm path lengths for direct measurement of sample volumes of less than 2.5 μl (down to 0.6 μl) for all life science applications. If required, these path lengths can be certified. Cells are available with Z heights of 8.5 mm or 15 mm to suit a wide range of instrument designs

Rectangular cells are used for most UV/VIS routine analysis. By far the most common type of cell, they have two windows clear and conform to international standard dimension. The 10mm pathlength size should fit most instruments that use rectangular cells. Available pathlengths are from 1mm to 100mm. Check with your instrument manual to see if you need an adaptor for longer pathlength cells.

Standard Rectangular cells are the most commonly cells used. The have two polished windows and a full interior width used in most instruments.

Cylindrical Cells are used where The spectrophotometer has a larger, circular light beam. Starna offers several configurations with pathlengths from 0.01 to 100mm. Check the links below for some of the many designs available.