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Xiamen Zeesan Biotech Co., Ltd.
Building 1, 3701 Xiang'An North Road Xiang'an District,
361101
Xiamen Fujian
China
China
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Our range of products
Product categories
- 02 Laboratory technology
- 02.09 Laboratory equipment
Laboratory equipment
- 02 Laboratory technology
- 02.18 Sampling systems
Sampling systems
- 03 Diagnostic tests
- 03.06 Genetic testing, molecular diagnostics
- 03.06.03 Polymerase chain reaction (PCR)
Polymerase chain reaction (PCR)
- Virus RNA Collection Kit
- Saliva RNA Sample Collection Kit
- Virus RNA Extraction Kit (manual kit)
- Lab-Aid 824s Nucleic Acid Extraction System
- Lab-Aid Virus RNA Extraction Kit
- SARS-CoV-2 Test Kit(Real-time PCR)-Liquid
- SARS-CoV-2 Test Kit(Real-time PCR)-Dry
- MeltPro® High Risk HPV Genotyping Assay
- MeltPro® Low Risk HPV Genotyping Assay
- MeltPro® MTB Test Kit
- MeltPro® MTB/RIF Test Kit
- Leukemia Fusion Genes (Q30) Screening Kit
- Real-Time PCR System（Gentier 48E）
- Real Time Quantitative Thermal Cycler（MA-6000）
- Sanity 2.0 System
Our products
Product category: Sampling systems, Polymerase chain reaction (PCR)
Virus RNA Collection Kit
Certificate:
NMPA, CE, FDA List
The Virus RNA Collection Kit provides an all-in-one system for the collection, stabilization and transportation of Viral sample.
Kit’s component: one perservation solution tube +one oropharyngeal swab + one nasopharyngeal swab
Sample type: Swab sample (oropharyngeal swab or nasopharyngeal swab) and BALF sample
Collection: Sample can be stored and transported under 25℃.
Inactivation: The perservation solution can inactivate the virus and protect users.
Storage: Collected sample is recommended to use within 14 days. For long-term storage, it should be stored at 2~8ºC and used within 1 month.
Intended use: for the collection, transportation and storage of samples (virus).
Innovation point: This product fully mixes the collected samples with virus lysis and viral nucleic acid preservation solution to achieve the lysis and inactivation of the virus in the sample, while effectively ensuring the stability of the virus nucleic acid in the sample during storage and transportation at room temperature.
NMPA, CE, FDA List
The Virus RNA Collection Kit provides an all-in-one system for the collection, stabilization and transportation of Viral sample.
Kit’s component: one perservation solution tube +one oropharyngeal swab + one nasopharyngeal swab
Sample type: Swab sample (oropharyngeal swab or nasopharyngeal swab) and BALF sample
Collection: Sample can be stored and transported under 25℃.
Inactivation: The perservation solution can inactivate the virus and protect users.
Storage: Collected sample is recommended to use within 14 days. For long-term storage, it should be stored at 2~8ºC and used within 1 month.
Intended use: for the collection, transportation and storage of samples (virus).
Innovation point: This product fully mixes the collected samples with virus lysis and viral nucleic acid preservation solution to achieve the lysis and inactivation of the virus in the sample, while effectively ensuring the stability of the virus nucleic acid in the sample during storage and transportation at room temperature.
Product category: Sampling systems, Polymerase chain reaction (PCR)
Saliva RNA Sample Collection Kit
Certificate: NMPA, CE, FDA List
Intended use: For the collection, transportation and storage of RNA from saliva samples.
Innovation point: Our company has several international patents for this product. This product adopts the pre-filled preservation solution integrated injection molding design, which can realize the direct mixing of the preservation fluid and the saliva sample to instantly inactivate the virus. It greatly protects the operator and the subject, increases the comfort of the subject, and is very convenient.
Intended use: For the collection, transportation and storage of RNA from saliva samples.
Innovation point: Our company has several international patents for this product. This product adopts the pre-filled preservation solution integrated injection molding design, which can realize the direct mixing of the preservation fluid and the saliva sample to instantly inactivate the virus. It greatly protects the operator and the subject, increases the comfort of the subject, and is very convenient.
Product category: Polymerase chain reaction (PCR)
Virus RNA Extraction Kit (manual kit)
The product is a RNA Extraction Manual kit, intended to be used by professional users, such as technicians and physicians who are trained in molecular biological techniques. Magnetic stands are required during the experiment. The kit provides high-quality RNA that is suitable for downstream applications, such as amplification or other enzymatic reactions.
Intended Use:
1) NMPA approved in China for clinical use
2) CE marked for IVD use in Europe
3) FDA List for IVD use in USA
Intended Use:
1) NMPA approved in China for clinical use
2) CE marked for IVD use in Europe
3) FDA List for IVD use in USA
Product category: Laboratory equipment, Polymerase chain reaction (PCR)
Lab-Aid 824s Nucleic Acid Extraction System
Certificate: NMPA, CE, FDA List
The Lab-Aid 824s Nucleic Acid Extraction System is proprietarily developed by Xiamen ZEESAN Biotech Co., Ltd, which is applicable for isolation and purification of nucleic acid from various medical and biological samples. The system adopts the mode of the 10-tubes cartridge, and is equipped with the functions of heating, UV disinfection, negative pressure of extraction operating room, etc. that is able to process 1~24 samples in a single run. The instrument has the characteristics of short extraction time, high extraction efficiency, high level of automation and suitable for various nucleic acid extraction kit of magnetic beads method. The intellectualized designed process is controlled by software completely that would auto-complete the nucleic acid isolation and purification process, which save the time and energy of laboratory technician and make the nucleic acid extraction simple. The system can be widely used in
fields of clinical gene research, molecular biological experiment and medicolegal expertise, etc.
The Lab-Aid 824s Nucleic Acid Extraction System is proprietarily developed by Xiamen ZEESAN Biotech Co., Ltd, which is applicable for isolation and purification of nucleic acid from various medical and biological samples. The system adopts the mode of the 10-tubes cartridge, and is equipped with the functions of heating, UV disinfection, negative pressure of extraction operating room, etc. that is able to process 1~24 samples in a single run. The instrument has the characteristics of short extraction time, high extraction efficiency, high level of automation and suitable for various nucleic acid extraction kit of magnetic beads method. The intellectualized designed process is controlled by software completely that would auto-complete the nucleic acid isolation and purification process, which save the time and energy of laboratory technician and make the nucleic acid extraction simple. The system can be widely used in
fields of clinical gene research, molecular biological experiment and medicolegal expertise, etc.
Product category: Polymerase chain reaction (PCR)
Lab-Aid Virus RNA Extraction Kit
Certificate: NMPA, CE, FDA List
Intended use: used for nucleic acid extraction, enrichment, purification and other steps. The processed product is used for clinical in vitro testing
Innovation: This reagent uses magnetic beads developed by our company. According to the unique separation function of magnetic beads, it provides an extremely simple operation procedure: sample lysis, magnetic bead adsorption, washing and elution. The reagents need to be used in conjunction with the Lab-Aid nucleic acid extractor produced by our company. Under the most suitable reagents and operating conditions, high-quality nucleic acids can be obtained.
Lab-Aid Virus RNA Extraction Kit utilizes magnetic beads technology for automated isolation and purification of genomic RNA from nasopharyngeal swab, oropharyngeal swab, sputum, bronchoalveolar lavage fluid (BALF) and stool swab. The product is intended to be used by professional users, such as technicians and physicians who are trained in molecular biological techniques. The kit provides high-quality RNA that is suitable for direct use in downstream applications, such as amplification or other enzymatic reactions. The Lab-Aid series isolation system performs all steps of the sample preparation procedure for up to 24 samples in a single run.
Intended use: used for nucleic acid extraction, enrichment, purification and other steps. The processed product is used for clinical in vitro testing
Innovation: This reagent uses magnetic beads developed by our company. According to the unique separation function of magnetic beads, it provides an extremely simple operation procedure: sample lysis, magnetic bead adsorption, washing and elution. The reagents need to be used in conjunction with the Lab-Aid nucleic acid extractor produced by our company. Under the most suitable reagents and operating conditions, high-quality nucleic acids can be obtained.
Lab-Aid Virus RNA Extraction Kit utilizes magnetic beads technology for automated isolation and purification of genomic RNA from nasopharyngeal swab, oropharyngeal swab, sputum, bronchoalveolar lavage fluid (BALF) and stool swab. The product is intended to be used by professional users, such as technicians and physicians who are trained in molecular biological techniques. The kit provides high-quality RNA that is suitable for direct use in downstream applications, such as amplification or other enzymatic reactions. The Lab-Aid series isolation system performs all steps of the sample preparation procedure for up to 24 samples in a single run.
Product category: Polymerase chain reaction (PCR)
SARS-CoV-2 Test Kit(Real-time PCR)-Liquid
Intended Use:
This kit is used for in vitro qualitative detection of novel coronavirus (SARS-CoV-2) ORF1ab and N gene in samples, including nasopharyngeal swab, oropharyngeal swab, bronchoalveolar lavage fluid and stool, for diagnosis of the COVID-19
infection, the suspected cluster cases and of the patients who need differential diagnosis of COVID-19 infection.
Principle of the Procedures:
This kit used a multiplex Taqman probe-based one-step reverse transcription polymerase chain reaction (RT-PCR), which
enables simultaneous qualitative detection of ORF1ab and N gene of SARS-CoV-2 as well as a non-human internal control
(Armored RNA for SUC2) in one reaction.
Instument:
The kit can be operated by the real-time PCR thermal cycler with FAM, HEX and ROX detection channels. Among them,
SLAN96S, SLAN 96P, ABI7500, LightCycler 480 and Bio-Rad CFX96 is highly recommended. ABI StepOne, StepOne Plus,
ABI 7500fast, ABI QuantStudio™ series, Mx3000P/Mx3005P, LightCycler 96 and Rotor-Gene series need to be tested prior
to use
This kit is used for in vitro qualitative detection of novel coronavirus (SARS-CoV-2) ORF1ab and N gene in samples, including nasopharyngeal swab, oropharyngeal swab, bronchoalveolar lavage fluid and stool, for diagnosis of the COVID-19
infection, the suspected cluster cases and of the patients who need differential diagnosis of COVID-19 infection.
Principle of the Procedures:
This kit used a multiplex Taqman probe-based one-step reverse transcription polymerase chain reaction (RT-PCR), which
enables simultaneous qualitative detection of ORF1ab and N gene of SARS-CoV-2 as well as a non-human internal control
(Armored RNA for SUC2) in one reaction.
Instument:
The kit can be operated by the real-time PCR thermal cycler with FAM, HEX and ROX detection channels. Among them,
SLAN96S, SLAN 96P, ABI7500, LightCycler 480 and Bio-Rad CFX96 is highly recommended. ABI StepOne, StepOne Plus,
ABI 7500fast, ABI QuantStudio™ series, Mx3000P/Mx3005P, LightCycler 96 and Rotor-Gene series need to be tested prior
to use
Product category: Polymerase chain reaction (PCR)
SARS-CoV-2 Test Kit(Real-time PCR)-Dry
This kit is used for in vitro qualitative detection of novel coronavirus (SARS-CoV-2) ORF1ab and N gene in samples, including nasopharyngeal swab, oropharyngeal swab, sputum, bronchoalveolar lavage fluid and stool, for diagnosis of the COVID-19 infection, the suspected cluster cases and of the patients who need differential diagnosis of COVID-19 infection.
Certificate:
FDA EUA, CE
Feature:
1. The dry reagent is convenient for transportation and storage, and the reagent has good stability.
2. The dry reagent version includes reagent formats that are suitable for most common models to meet the needs of large-throughput sample testing, and it also includes reagent formats that are suitable for automated testing instruments (all-in-one) to meet the needs of clinical POCT.
3. The ordinary version of the reaction reagent is a pre-packed dry reagent, and does not require a liquid dispensing process. You can directly add samples for each test hole, which is easy to operate. The all-in-one version of dry reagents can be adapted to the all-in-one version. After adding samples, the instrument automatically completes the extraction and detection process, which greatly reduces manual operations.
Certificate:
FDA EUA, CE
Feature:
1. The dry reagent is convenient for transportation and storage, and the reagent has good stability.
2. The dry reagent version includes reagent formats that are suitable for most common models to meet the needs of large-throughput sample testing, and it also includes reagent formats that are suitable for automated testing instruments (all-in-one) to meet the needs of clinical POCT.
3. The ordinary version of the reaction reagent is a pre-packed dry reagent, and does not require a liquid dispensing process. You can directly add samples for each test hole, which is easy to operate. The all-in-one version of dry reagents can be adapted to the all-in-one version. After adding samples, the instrument automatically completes the extraction and detection process, which greatly reduces manual operations.
Product category: Polymerase chain reaction (PCR)
MeltPro® High Risk HPV Genotyping Assay
MeltPro® High Risk HPV Genotyping Assay
This HPV test kit is a qualitative in vitro test used for HPV genotyping and cervical cancer screening using cervical cells collected by swab, TCT or LCT. This test utilizes Polymerase Chain Reaction (PCR) for DNA amplification and nucleic acid hybridization for the detection of high-risk HPV types in one reaction. This test specifically identifies 14 high-risk HPV types, including HPV-16, HPV-18, HPV-31, HPV-33, HPV-35, HPV-39, HPV-45, HPV-51, HPV-52, HPV-56, HPV-58, HPV-59, HPV-66, and HPV-68.
The test is indicated 1) to screen patients age 21 and older with ASU-US (atypical squamous cells of undetermined significance) cervical cytology test results to determine the need for referral to colposcopy, and assess the presence of high-risk HPV, to guide patient management together with the physician’s assessment of cytology history, other risk factors, and professional guidelines; 2) to use with cervical cytology to adjunctively screen to assess the presence of high risk HPV types in women age 30 and older, considering other risk factors such as cytology history to guide patient management.
This HPV test kit is a qualitative in vitro test used for HPV genotyping and cervical cancer screening using cervical cells collected by swab, TCT or LCT. This test utilizes Polymerase Chain Reaction (PCR) for DNA amplification and nucleic acid hybridization for the detection of high-risk HPV types in one reaction. This test specifically identifies 14 high-risk HPV types, including HPV-16, HPV-18, HPV-31, HPV-33, HPV-35, HPV-39, HPV-45, HPV-51, HPV-52, HPV-56, HPV-58, HPV-59, HPV-66, and HPV-68.
The test is indicated 1) to screen patients age 21 and older with ASU-US (atypical squamous cells of undetermined significance) cervical cytology test results to determine the need for referral to colposcopy, and assess the presence of high-risk HPV, to guide patient management together with the physician’s assessment of cytology history, other risk factors, and professional guidelines; 2) to use with cervical cytology to adjunctively screen to assess the presence of high risk HPV types in women age 30 and older, considering other risk factors such as cytology history to guide patient management.
Product category: Polymerase chain reaction (PCR)
MeltPro® Low Risk HPV Genotyping Assay
MeltPro® High Risk HPV Genotyping Assay
This HPV test kit is a qualitative in vitro test used for HPV genotyping using cervical cells collected by swab, TCT or LCT. This test utilizes Polymerase Chain Reaction (PCR) for DNA amplification and nucleic acid hybridization for the detection of low-risk HPV types in one reaction. This test specifically identifies 14 low-risk HPV types, including HPV-11, HPV-6,HPV-53, HPV-26, HPV-42, HPV-69, HPV-81, HPV-43, HPV-40, HPV-72, HPV-44, HPV-61, HPV-54 and HPV-70. The test is indicated to use with cervical cytology to adjunctively screen to assess the presence of low risk HPV types in women age 30 and older.
It’s based on the technology of multi-color melting curve analysis (MMCA). HPV genotypes are identified by the different Tm values of hybridizing PCR products with the fluorescent probes. The principle of this test is shown in figure 1: several HPV type-specific probes are designed with the same fluorophore and quencher that will be detected in one single channel. It was designed that the T m value of each probe-target hybrid differs with varied length and G/C content of the probe. According to this design, 14 low-risk HPV genotypes can be accurately distinguished in a single reaction.
Special PCR Freeze-dry reagent:
1, Easy to use: pre-loaded kit
2, Easy to ship: transport at room temperature
This HPV test kit is a qualitative in vitro test used for HPV genotyping using cervical cells collected by swab, TCT or LCT. This test utilizes Polymerase Chain Reaction (PCR) for DNA amplification and nucleic acid hybridization for the detection of low-risk HPV types in one reaction. This test specifically identifies 14 low-risk HPV types, including HPV-11, HPV-6,HPV-53, HPV-26, HPV-42, HPV-69, HPV-81, HPV-43, HPV-40, HPV-72, HPV-44, HPV-61, HPV-54 and HPV-70. The test is indicated to use with cervical cytology to adjunctively screen to assess the presence of low risk HPV types in women age 30 and older.
It’s based on the technology of multi-color melting curve analysis (MMCA). HPV genotypes are identified by the different Tm values of hybridizing PCR products with the fluorescent probes. The principle of this test is shown in figure 1: several HPV type-specific probes are designed with the same fluorophore and quencher that will be detected in one single channel. It was designed that the T m value of each probe-target hybrid differs with varied length and G/C content of the probe. According to this design, 14 low-risk HPV genotypes can be accurately distinguished in a single reaction.
Special PCR Freeze-dry reagent:
1, Easy to use: pre-loaded kit
2, Easy to ship: transport at room temperature
Product category: Polymerase chain reaction (PCR)
MeltPro® MTB Test Kit
MeltPro®Mycobacterium Tuberculosis Test Kit
Mycobacterium tuberculosis Test Kit is suitable for rapid, qualitative detection of Mycobacterium tuberculosis complex (MTBC) in vitro diagnostic use. Mycobacterium tuberculosis Test Kit is based on the Real-time PCR to detect the specific IS6110 gene.
At the same time, an exogenous internal control was added in the system for amplification quality control.
Mycobacterium tuberculosis Test Kit is suitable for rapid, qualitative detection of Mycobacterium tuberculosis complex (MTBC) in vitro diagnostic use. Mycobacterium tuberculosis Test Kit is based on the Real-time PCR to detect the specific IS6110 gene.
At the same time, an exogenous internal control was added in the system for amplification quality control.
Product category: Polymerase chain reaction (PCR)
MeltPro® MTB/RIF Test Kit
MeltPro® Mycobacterium tuberculosis Rifampin-resistance Mutation Test Kit
Mycobacterium tuberculosis Rifampin-resistance Mutation Test is based on the Probe-based Melting
Curve Analysis. According to the change in Tm value between targets and the corresponding wild-type
probe sequences, the test detects the mutations in rpoB gene (codons 507~533), which reports rifam-
pin-resistance information.
Detection region: mutations in rpoB codons 507~533 (81 bp) (coverage rate: 95% of all rifampicin-resistant mutants)
Principle of Probe-Based Melting Curve Analysis
Probe-based melting curve analysis is based on melting temperature generated by thermal denaturation of
the probe-target hybrid. Melting curve plot of fluorescence (F) versus temperature (T) is transformed into
melting peak by plotting -dF/dT versus temperature. The hybridization probe with fully matched wild-type
target gives the highest Tm value. With matched mutant-type target, it gives the lower T m value.
Mutation is detected as Tm deviation (△Tm ) compared to the wild-type hybrid.
Intended use: NMPA approved in China for clinical use, CE marked for IVD use in Europe.
Mycobacterium tuberculosis Rifampin-resistance Mutation Test is based on the Probe-based Melting
Curve Analysis. According to the change in Tm value between targets and the corresponding wild-type
probe sequences, the test detects the mutations in rpoB gene (codons 507~533), which reports rifam-
pin-resistance information.
Detection region: mutations in rpoB codons 507~533 (81 bp) (coverage rate: 95% of all rifampicin-resistant mutants)
Principle of Probe-Based Melting Curve Analysis
Probe-based melting curve analysis is based on melting temperature generated by thermal denaturation of
the probe-target hybrid. Melting curve plot of fluorescence (F) versus temperature (T) is transformed into
melting peak by plotting -dF/dT versus temperature. The hybridization probe with fully matched wild-type
target gives the highest Tm value. With matched mutant-type target, it gives the lower T m value.
Mutation is detected as Tm deviation (△Tm ) compared to the wild-type hybrid.
Intended use: NMPA approved in China for clinical use, CE marked for IVD use in Europe.
Product category: Polymerase chain reaction (PCR)
Leukemia Fusion Genes (Q30) Screening Kit
Leukemia Fusion Genes (Q30) Screening Kit is a qualitative in vitro diagnostic test for screening of 30 fusion genes
resulted from chromosome translocations involved in chronic and acute leukemia. All the 30 fusion genes include more than
155 clinically relevant chromosomal breakpoints [1-9] . The kit detects RNA transcripts of fusion genes extracted from human
bone marrow or whole blood samples using a RT-qPCR procedure.
The fusion gene detected by the kit allows professionals to be more aware of the patient`s prognosis and provides
professionals important insights into the treatment planning.
Intended use: CE marked for IVD use in Europe
resulted from chromosome translocations involved in chronic and acute leukemia. All the 30 fusion genes include more than
155 clinically relevant chromosomal breakpoints [1-9] . The kit detects RNA transcripts of fusion genes extracted from human
bone marrow or whole blood samples using a RT-qPCR procedure.
The fusion gene detected by the kit allows professionals to be more aware of the patient`s prognosis and provides
professionals important insights into the treatment planning.
Intended use: CE marked for IVD use in Europe
Product category: Laboratory equipment, Polymerase chain reaction (PCR)
Sanity 2.0 System
No PCR laboratory required, suitable for emergency departments of large hospitals or small to medium-sized medical institutions
Simultaneous extraction and PCR detection
Small-scale POCT fully-automatic molecular diagnosis platform, one-button operation, without manual intervention
The fastest time of reporting positive results is 40 minutes
Realizing one machine for multiple purposes.
Adapt to multiple tests such as respiratory pathogen, leukemia, tuberculosis, etc.
Simultaneous extraction and PCR detection
Small-scale POCT fully-automatic molecular diagnosis platform, one-button operation, without manual intervention
The fastest time of reporting positive results is 40 minutes
Realizing one machine for multiple purposes.
Adapt to multiple tests such as respiratory pathogen, leukemia, tuberculosis, etc.
About us
Company portrait
Since 2010, Zeesan Biotech is a rapidly growing biomedical company specialized in the development and production of molecular diagnostics related kits, instruments and reagents. The headquarters of Zeesan are located in Xiamen Torch Industry Park (Xiang’an) and it has offices in Beijing, Shanghai, Guangzhou and New Jersey (USA). Zeesan is a technology-driven company that prides itself on its scientific excellence. From our leading MeltPro® series molecular diagnostics products to our well-recognized automated DNA extraction machines and to our highly praised visible-light gel electrophoresis system, each of our products embodies the creativity of our excellent scientists, who are working hard to continuously bring novel products to the China and world markets. Zeesan now has over 1700 square meters Certificated Clean Factory building equipped with advanced instruments and core facilities. The production process is strictly regulated by the IVD Quality Management System (13485 equivalent system in China), which forms the solid base for the high quality of our products.
Zeesan holds the mission of “For Life We Care” and is committed to the development and marketing the best products for molecular diagnostics.. The major products of our company are now widely used in hospitals, CDC, CIQ, and universities etc. As a translational base for Research Engineering Centre of Molecular Diagnostics, Ministry of Education (China), our company also plays an active role bridging collaborations between industry, academy and research. The status of Zeesan is already recognized as being the undertaker of several important national projects in China, such as the Important National Science & Technology Specific Project and the National High Technology Research and Development Program (‘‘863’’ Program).
Zeesan holds the mission of “For Life We Care” and is committed to the development and marketing the best products for molecular diagnostics.. The major products of our company are now widely used in hospitals, CDC, CIQ, and universities etc. As a translational base for Research Engineering Centre of Molecular Diagnostics, Ministry of Education (China), our company also plays an active role bridging collaborations between industry, academy and research. The status of Zeesan is already recognized as being the undertaker of several important national projects in China, such as the Important National Science & Technology Specific Project and the National High Technology Research and Development Program (‘‘863’’ Program).