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Meridian Bioscience, Inc.

5171, Wilfong Road, 38134 Memphis, TN
USA

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Contact

Ph.D. Christian Zimmerman

Sales Director EMEA Life Science

Phone
+49 162 10 10 405

Email
Christian.Zimmermann@MeridianLifeScience.com

Olivier Bezombes

Snr. Business Development Manager, SW Europe, Life Science

Phone
+33 (0)6 11 82 21 82

Email
olivier.bezombes@meridianlifescience.com

Marieke Koehler

Business Development Manager West Germany, Life Science

Phone
+49 (0) 162 101 5721

Email
Mareike.koehler@meridianlifescience.com

Ph.D. James Youell

Business Development Manager UK and Scandinavia, Life Science

Phone
+44 7941 710717

Email
James.Youell@MeridianLifeScience.com

Benjamin Sanyaolu

Business Development Manager – EMEA Distribution, LIFE SCIENCE

Phone
+44 (0) 7941 262 175

Email
benjamin.sanyaolu@meridianlifescience.com

Sarah Panton

Senior Account Manager, UK, IE, NL, BE, Life Science

Phone
+44 (0) 7941 199190

Email
sarah.panton@meridianlifescience.com

Katharina Hess

Inside Sales

Phone
+ 49 (0) 711 50490920

Email
katharina.hess@meridianlifescience.com

Visit us

Unsettled / NN

19.11.2020

Topic

14:00 - 15:00

Lyo-Ready and Air-Dryable qPCR/RT-qPCR Mixes Q&A

Ask the Expert 2 pm (GMT)

Please copy and past the link below into your web browser to join 

https://teams.microsoft.com/l/meetup-join/19%3ameeting_MWY5ZTUyYzMtNGJmYy00MjUyLTgyYTMtMDgyMTFmMmZkYzA2%40thread.v2/0?context=%7b%22Tid%22%3a%22bd128071-3625-4b5b-8d09-a89273e4c5c8%22%2c%22Oid%22%3a%2225f98b76-8da7-4697-a3ae-07e779b1da0a%22%7d

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Our products

Product category: Polymerase chain reaction (PCR)

Reagents for Molecular Diagnostic Assays (Optimized qPCR/RT-qPCR Mixes, Enzymes, dNTPs, Extraction Controls and more)

Meridian is a primary manufacturer of specialized high-quality molecular reagents and offers solutions to a wide range of industries to diagnose and treat diseases, discover new therapeutics or develop tests for environmental, food and cosmetic safety.

Products include optimized qPCR and RT-qPCR master mixes for creating ambient temperate assays through lyophilization or air-drying, extraction-free qPCR/RT-qPCR mixes and aptamer hot-start enzymes include a high-specificity Pfu.  Please click on the link below to view a catalog of our full molecular range.

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Product category: Polymerase chain reaction (PCR)

Inhibitor-Tolerant qPCR & RT-qPCR Mixes

A variety of different inhibitors inherent to clinical and environmental samples can negatively impact the sensitivity and accuracy of a molecular assay. Conventionally, to overcome this, specimens undergo processing prior to testing.  However, extraction technologies are not 100% efficient which can impact the amount of target nucleic acid available for testing, and some inhibitors can co-elute following purification and induce false-negative assay results.

Meridian’s Inhibitor-Tolerant qPCR/RT-qPCR formulations are designed for developing qualitative multiplex assays that require minimal sample processing and fast turn-around times (TAT). The mixes can be used for direct amplification from crude lysates or inhibitor-rich samples such as urine, cerebral spinal fluid (CSF), blood, sputum, saliva and stool.

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Product category: Polymerase chain reaction (PCR)

Enzymes & Mixes for Creating Ambient-Temperature Molecular Assays using Lyophilization or Air Drying Technologies

Molecular diagnostic tests are progressively moving towards lyophilized and air-dried formats. There are several advantages for this, including room temperature shipping and storage, extended shelf-life and increased flexibility in sample volume. In order to be compatible with drying however, enzyme preparations must be glycerol-free and include specialized excipients that preserve the mixture as it is exposed to various conditions including freezing, temperature ramps, vacuum and dehydration. An ideal lyophilization formulation for example, should stabilize an enzyme in a freezedried format and allow very fast rehydration and  reactivation of the enzyme preparations, without impacting its performance post rehydration.

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Product category: Other infectious immunology testing

COVID-19 Antigens & Antibodies

Rapid antigen tests can provide a result in minutes and can be produced at a lower cost in large scales. However, the performance of rapid antigen test is limited by the sensitivity of the antibodies used. Meridian’s monoclonal antibodies are highly sensitive for the detection of SARS-CoV-2 and they do not cross-react with seasonal coronavirus strains. They are ideal for developing reliable and sensitive rapid lateral flow antigen assays for the detection of active COVID-19 infections.

Serologic tests are an important tool for monitoring the evolution of an outbreak. Specifically, IgG/IgM antibody tests are  essential for identifying previously undiagnosed infections in the asymptomatic population. Meridian’s recombinant antigens are
expressed in human mammalian cells and insect cells using proprietary expression and purification technologies. Expression in either human or insect cells provides for post-translational modifications such as glycosylation and phosphorylation which can offer significant performance advantages over E. coli expressed formats.

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Product category: Other infectious immunology testing

Infectious Disease Antibodies & Antigens

Infectious diseases are a leading cause of death worldwide, particularly in low income countries and especially in young children. The leading killers are HIV/AIDS, tuberculosis and malaria, however, lower respiratory infections (including pneumonia) and diarrheal diseases are also 2 of the top 10 causes of death globally according to the most recent survey by the World Health Organization (WHO).

Meridian has a large range (over 2,000 products) of antigens and antibodies to tropical diseases, ToRCH & childhood diseases, STDs, repiratory diseases and gastrointestinal disorders.   Antibody pairing informaiton is available with a focus on rapid lateral flow applications.

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Product category: Other infectious immunology testing

Immunoassay Blockers for HAMA, HA and Rheumatoid Factor Interference

Immunoassay blockers are used in diagnostic assays to reduce non-specific binding and other interference that can lead to false positive results. Specifically, interference from human anti-mouse antibodies (HAMA), rheumatoid factor (RH) and heterophilic antibodies (HA) are a major concern in both paired monoclonal sandwich assays and competitive assays. Specialized blockers are required in these assays to reduce any interference and to ensure the assay’s accuracy.

Meridian’s range of blockers includes both active blockers such TRU Block™ and passive blockers such as Mouse IgG. Specifically, TRU Block™ ULTRA (a next-generation HAMA blocker) is the result of years of R&D aimed at creating the most powerful immunoassay interference blocker in the market. It provides a broad coverage against HAMA, HA and RF and works in several assay types including ELISA and Lateral Flow. IVD manufacturers are able to use this active blocker at reduced concentrations and achieve higher assay performance.

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Product category: Other infectious immunology testing

Antigens & Antibodies for Cancer, Cardiac, Autoimmune, Hormones, Vet Health and More

Meridian has a large range of antigens and antibodies to cancer, cardiac, autommimmune, and endocrine disorders as well as a specific reagents for managing vet health.  Please visit the link below to our full product line to see the entire range.  Antibody pair information is also available.

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About us

Company details

Meridian Life Science, Inc. is a leading large scale manufacturer of antibodies, viral antigens, recombinant proteins, PCR Enzymes, nucleotides and critical assay reagents.

Meridian has been providing innovative life science solutions and building trusted partnerships for over 40 years. The company's focus is to offer products and services that help to advance the development of diagnostic assays.

  • Commercial scale manufacturing of antigens and antibodies with protein purification expertise
  • Full line of immunoassay reagents including blockers, antigens and antibodies
  • Large scale production of reagents for molecular assays
  • Technical support with assay development experience
  • Dedicated R&D and Manufacturing Teams
  • Robust and Mature Quality System
  • Contract R&D, process development, and manufacturing services.
 
Extensive Capabilities and Services
 
Immunodiagnostics
  • Antigens & Antibodies
  • Recombinant Proteins
  • Blocking Reagents
Contract Services
  • Antigens & Antibodies
  • Cell & Viral Banking
PCR Amplification
  • Nucleotides
  • Enzymes
  • PCR / qPCR Reagents
  • Customized Master Mixes

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Company data

Sales volume

200-499 Mio US $

Number of employees

500-999

Foundation

1977

Area of business

Diagnostics

Company information as a PDF file